1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected with bortezomib, a proteasome inhibitor Utilized in the treatment method of several myeloma. Its synthesis or study is essential for making sure the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-one): A critical compound within the synthesis of imatinib, a drug that targets specific different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the production approach and ensuring large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to deal with breast GeMcitabine InterMediate T6 most cancers, and these intermediates are linked to its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the remedy of breast cancer. Several intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers which include ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the treatment method of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-9): This compound is involved in the synthesis of adamantane derivatives, which have different apps, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-4 to control blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which might be Employed in meals, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor CAS NO.949023-16-9 within the synthesis of canagliflozin, a medication utilized to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).